Search results for " hemoglobinopathies"

showing 3 items of 3 documents

Treatment of hepatitis C virus infection with direct-acting antiviral drugs is safe and effective in patients with hemoglobinopathies

2017

Progression of liver fibrosis in patients with hemoglobinopathies is strongly related to the severity of iron overload and the presence of chronic hepatitis C virus (HCV) infection. Effective iron chelation therapy and HCV infection eradication may prevent liver complications. The European Association for the Study of the Liver guidelines recommend interferon-free regimens for the treatment of HCV infection in patients with hemoglobinopathies. However, data regarding the use of direct-acting antiviral drugs (DAAs) in this patient population are few. This observational study evaluated the safety and efficacy of therapy with DAAs in an Italian cohort of patients with hemoglobinopathies, chron…

Liver CirrhosisAdultMalemedicine.medical_specialtyIron OverloadThalassemiaHepatitis C virusLiver CirrhosiIron Chelating Agentsmedicine.disease_causeAntiviral AgentsGastroenterologyVirus03 medical and health sciencesLiver disease0302 clinical medicineInternal medicinemedicinechronic hepatitis CHumansHematology hemoglobinopathies chronic hepatitis C direct antiviral agentsChelation therapyChronicAntiviral AgentSettore MED/12 - GastroenterologiaHematologybusiness.industrydirect antiviral agentsAdult; Antiviral Agents; Female; Hemoglobinopathies; Hepatitis C Chronic; Humans; Iron Chelating Agents; Iron Overload; Liver Cirrhosis; Male; Middle Aged; Treatment Outcome; HematologyHepatitis CHematologyHepatitis C ChronicMiddle Agedmedicine.diseaseHepatitis CHemoglobinopathiesHemoglobinopathieIron Chelating AgentTreatment Outcome030220 oncology & carcinogenesisImmunologyCohort030211 gastroenterology & hepatologyFemalebusinessHuman
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Study on the efficacy of Rapamicin as an inducer of fetal hemoglobin in primary erythroid cultures from patientes with hemoglobinopathies

2011

Rapamicin hemoglobinopathies
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Study on the efficacy of Rapamicin as an inducer of fetal hemoglobin in primary erythroid cultures from patientes with hemoglobinopathies

2009

Rapamicin hemoglobinopathies
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